New Information on Hepatology-Dr. Wu's liver diseases (Hepatitis, ...)

Chinese Medical Information Portal Website (Taiwan Medical Network-TMN) - OldDoc Wu's Series

(Established in March 1996) liver-diseases

New Information on Hepatology

Dr. Wu's Liver diseases
for professionals (medical students and residents)

(by Jau-Shin WU, M.D., Ph.D.)

(Posted Sep. 16, 1996; Updated May 14, 2009)

#(2009) Hepatology - A clinical textbook (Free download) - (501 pp, PDF, 9 MB) Editors�GStefan Mauss�AThomas Berg�AJuergen Rockstroh�AChristoph Sarrazin�AHeiner Wedemeyer�C(This textbook was made possible through unrestricted educational grants from Hoffmann�VLa Roche, Germany �V www.Roche.com; Gilead Sciences, Germany �V www.Gilead.com)
#(2009) 2-Year GLOBE trial results: telbivudine Is superior to lamivudine in patients with chronic hepatitis B. by Liaw YF, et al. Gastroenterology. 2009 Feb;136(2):486-95
#(2009) Hepatitis B: A global health challenge. by RJ. Fontana. Gastroenterology February 2009 (Vol. 136, Issue 2, Pages 389-392)
# (2009) hepatitis B Infection. by Yun-Fan Liaw and Prof Chia-Ming Chu.
The Lancet, Volume 373, Issue 9663, Pages 582 - 592, 14 February 2009
#(2007)Physician's guide to chronic hepatitis B.by the Asian Liver Center at Stanford University.
# (2004) Screening for Hepatitis C Virus Infection: A Review of the Evidence for the U.S. Preventive Services Task ForceRoger Chou, MD; Elizabeth C. Clark, MD, MPH; and Mark Helfand, MD, MPH
Annals 2004 141: 576.

#Non-alcoholic fatty liver disease: a brief review. van Hoek B.
Scand J Gastroenterol Suppl. 2004;(241):56-9.

#Asian-Pacific consensus statement on the management of chronic hepatitis B: An update. Liaw YF, Leung N, Guan R, Lau GK and Merican I
J of Gastroenterology and Hepatology. 2003; 18: 239-245.

#Hepatitis flares and hepattis B e antigen seroconversion: Implication in ant-hepatitis B virus therapy. Liaw YF:
J of Gastroenterology and Hepatology. 2003; 18: 246-256.

#FDA APPROVES NEW TREATMENT FOR CHRONIC HEPATITIS B ---
USA-FDA Talk paper -- September 20, 2002
# Update in Hepatology --- Eugene R. Schiff, MD
(Annals of Internal Medicine, 21 March 2000. 132:460-466.)
# International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis (PDF: need acrobat reader)
F.Alvarez, P.A.Berg, F.B.Bianchi, L.Bianchi, A.K.Burroughs, E.L.Cancado, R.W.Chapman, W.G.E.Cooksley, A.J.Czaja, V.J.Desmet, P.T.Donaldson, A.L.W.F.Eddleston, L.Fainboim, J.Heathcote, J-C.Homberg, J.J.Hoofnagle, S.Kakumu, E.L.Krawitt, I.R.Mackay, R.N.M.MacSween, W.C.Maddrey, M.P.Manns, I.G.McFarlane, K-H.Meyer zum Buschenfelde, G.Mieli-Vergani, Y.Nakanuma, M.Nishioka, E.Penner, G.Porta, B.C.Portmann, W.D.Reed, J.Rodes, S.W.Schalm, P.J.Scheuer, E.Schrumpf, T.Seki, G.Toda, T.Tsuji, N.Tygstrup, D.Vergani and M.Zeniya (J of Hepatology; 1999 -- Vol 31: 929-938)
# Lamivudine as Initial Treatment for Chronic Hepatitis B in the United States
Jules L. Dienstag, Eugene R. Schiff, Teresa L. Wright, Robert P. Perrillo, Hie-Won L. Hann, Zachary Goodman, Lynn Crowther, Lynn D. Condreay, Mary Woessner, Marc Rubin, Nathaniel A. Brown, for the U.S. Lamivudine Investigator Group(New Engl J Med; October 21, 1999 -- Vol. 341, No. 17 , 1256-1263)
# Viral clearance without destruction of infected cells during acute HBV infection.
Guidotti LG, Rochford R, Chung J, Shapiro M, Purcell R, Chisari FV(Science 1999 Apr 30;284(5415):825-9)
# Pretreatment Evaluation of Chronic Hepatitis C Risks, Benefits, and Costs
John B. Wong, MD; William G. Bennett, MD; Raymond S. Koff, MD; Stephen G. Pauker, MD (JAMA-- Dec. 23/30, 1998; Vol. 280,No.24)
# Combination Therapy for Hepatitis C Infection (Editorial -- T. Jake Liang, M.D. National Institutes of Health )
( N Engl J Med -- November 19, 1998 -- Volume 339, Number 21)
# Interferon Alfa-2b Alone or in Combination with Ribavirin for the Treatment of Relapse of Chronic Hepatitis C
Gary L. Davis, Rafael Esteban-Mur, Vinod Rustgi, John Hoefs, Stuart C. Gordon, Christian Trepo, Mitchell L. Shiffman, Stefan Zeuzem, Antonio Craxi, Mei-Hsiu Ling, Janice Albrecht, for the Hepatitis Interventional Therapy Group (N Engl J Med 1998;339:1493-9.)
# Interferon Alfa-2b Alone or in Combination with Ribavirin as Initial Treatment for Chronic Hepatitis C
John G. McHutchison, Stuart C. Gordon, Eugene R. Schiff, Mitchell L. Shiffman, William M. Lee, Vinod K. Rustgi, Zachary D. Goodman, Mei-Hsiu Ling, Susannah Cort, Janice K. Albrecht, for the Hepatitis Interventional Therapy Group ;(N Engl J Med 1998;339:1485-92.)
# Presence of a newly described human DNA virus (TTV) in patients with liver disease.
Nikolai V Naoumov, Elena P Petrova, Mark G Thomas, Roger Williams. Institute of Hepatology, Department of Medicine (N V Naoumov MRCPath, E P Petrova PhD, Prof R Williams FRCP); and Departments of Biology and Anthropology (M G Thomas PhD), University College London Medical School, London, UK; (Lancet 1998; 352: 195-97)
# Detection of a novel DNA virus (TT virus) in blood donors and blood products
Simmonds, F Davidson, C Lycett, L E Prescott, D M MacDonald, J Ellender, P L Yap, C A Ludlam, G H Haydon, J Gillon, L M Jarvis Department of Medical Microbiology, University of Edinburgh (P Simmonds MRCPath, C Lycett BSc, L E Prescott PhD, D M MacDonald BSc, J Ellender MA); Edinburgh and South East Scotland Blood Transfusion Service, Edinburgh (F Davidson PhD, P L Yap FRCPath, J Gillon FRCPE, L M Jarvis PhD), Departments of Haematology and Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK (G H Haydon MRCP);Lancet 1998; 352: 191-95.
# Irregular regeneration of hepatocytes and risk of hepatocellular carcinoma in chronic hepatitis and cirrhosis with hepatitis-C-virus infection.
Shibata M, Morizane T, Uchida T, Yamagami T, Onozuka Y, Nakano M, Mitamura K, Ueno Y ;Lancet: 1998, June 13; 351(9118):1773-1777
"Tutorial for evaluating irregular regeneration in liver biopsy" by Toshikazu Uchida, MD, Minoru Shibata, MD, and Toshio Morizane, MD. January 11, 1999.
# One year trial of Lamivudine for chronic hepatitis B:
Ching-Lung Lai, Rong-Nan Chien, Nancy W.Y. Leung, Ting-Tsung Chang, Richard Guan, Dar-In Tai, Keng-Yeen Ng, Pui-Chee Wu, Julie C. Dent, Judy Barber, Sally L. Stephenson, D. Fraser Gray, for the Asia Hepatitis Lamivudine Study Group ;NEJM: 1998, 339:61.
# Fulminant hepatitis associated with hepatitis A virus superinfection in patient with chronic hepatitis C:
Sandro Vento, Tiziana Garofano, Carlo Renzini, Francesca Cainelli, Ferruccio Casali, Giancarlo Ghironzi, Teresa Ferraro, Ercole Concia ;NEJM: 1998, 338:286.
# Safety and immunogenecity of hepatitis A vaccine in patient with chronic live disease:
EMMET B. KEEFFE,1 STEN IWARSON,2 BRIAN J. MCMAHON,3 KAREN L. LINDSAY,4 RAYMOND S. KOFF,5 MICHAEL MANNS,6 RENATE BAUMGARTEN,7 MANFRED WIESE,8 MARC FOURNEAU,9 ASSAD SAFARY,9 RALF CLEMENS,9 AND DAVID S. KRAUSE10 ;Hepatology, 1998; 27:881.
# A novel virus (TTV) associated with elevated transaminase level in posttransfusion hepatitis of unknown etiology:
Nishizawa T, Okamoto H, Konishi K, Yoshizawa H, Miyakawa Y, Mayumi M; Biomchemical and biophysical reseaarch communications, 1997; 241:92-97.
# Mutations of the X region of hepatitis B virus and their clinical implications.
Uchida T, Saitoh T, Shinzawa H; Pathol Int 1997 Apr;47(4):183-193
# Hepatitis C virus is frequently coinfected with serum marker-negative hepatitis B virus: probable replication promotion of the former by the latter as demonstrated by in vitro cotransfection:
Uchida T, Kaneita Y, Gotoh K, Kanagawa H, Kouyama H, Kawanishi T, Mima S; J. Med. Virol, 1997; 52:399-405.
# Hepatitis B virus X gene mutation asociated with the majority of serologically "silent" non-b, non-c chronic hepatitis:
Fukuda R, Ishimura N, Kushiyama Y, Moriyama N, Ishihara S, Chowdhury A, Tokuda A, Sakai S, Akagi S, Watanabe M, Fukumoto S ;Microbiol Immunol, 1996; 40:481-8.
# Seroepidemiology of Hepatitis B Virus Infection in Children Ten Years of Mass Vaccination in Taiwan
Huey-Ling Chen, MD; Mei-Hwei Chang, MD; Yen-Hsuen Ni, MD; Hong-Yuan Hsu, MD, PhD; Ping-Ing Lee, MD; Chin-Yun Lee, MD; Ding-Shinn Chen, MD ;JAMA. 1996;276:906-908.
# Universal Hepatitis B Vaccination in Taiwan and the Incidence of Hepatocellular Carcinoma in Children
Mei-Hwei Chang, Chien-Jen Chen, Mei-Shu Lai, Hsu-Mei Hsu, Tzee-Chung Wu, Man-Shan Kong, Der-Cherng Liang, Wen-Yi Shau, Ding-Shinn Chen, for the Taiwan Childhood Hepatoma Study Group ;NEJM, 1997; 336:1855.

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(By Jau-Shin Wu, M.D.; Posted Sep. 16, 1996; Revised May 12, 2009)

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