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Chinese Medical Information Portal Website (Taiwan Medical Network-TMN) - OldDoc Wu's Series
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(Established in March 1996)
liver-diseases
Portal hypertension

吳昭新 醫師 編著 (by Jau-Shin WU, M.D., Ph.D.)
(Posted Sep. 16, 1996; Updated May 14, 2009)

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Portal hypertension

Any increase in the portal vein pressure (12 mm Hg or greater) due to anatomic or functional obstruction to blood flow in the portal venous system. Many conditions are associated with portal hypertension, of which cirrhosis is the most common cause. Indicators of portal hypertension are: esophageal varices, enlarged veins on the anterior abdominal wall (caput Medusae), and ascites.

Classification (1)

  1. PRESINUSOIDAL
    • extrahepatic:
      • portal vein obstruction (extrinsic compression, phlebitis, OC, coagulopathy, tumor invasion, pancreatitis, neonatal omphalitis)
      • dynamic: traumatic/neoplastic arterioportal fistula
      • segmental portal HTN: splenic/SMV occlusion
    • intrahepatic (obstruction of portal venules):
      • congenital hepatic fibrosis
      • primary biliary cirrhosis
      • Wilson's disease
      • schistosomiasis
      • sarcoid
      • myelofibrosis
      • idiopathic noncirrhotic fibrosis
      • reticuloendotheliosis
      • Felty syndrome
      • chronic malaria
      • toxic fibrosis (arsenic, copper, PVC vapors)
  2. SINUSOIDAL
    • cirrhosis
    • sclerosing cholangitis
  3. POSTSINUSOIDAL
    • Budd-Chiari syndrome
    • constrictive pericarditis
    • congestive heart failure

Classification (2)