Chinese Medical Information Portal Website (Taiwan Medical Network-TMN) - OldDoc Wu's Series
(Established in March 1996)
Chronic Hepatitis (staging)
Dr. Wu's Liver diseases
for professionals (medical students and residents)

(by Jau-Shin WU, M.D., Ph.D.)
(Posted Sep. 16, 1996; Updated May 14, 2009)


Chronic Hepatitis (staging)

For consumers:

(Key words: chronic hepatitis, staging)

  • Evaluation of the severity of the chronic hepatitis is made according to the amount of fibrosis and existence of cirrhosis in the liver on histological examination of a biopsied liver tissue.

For professionals:

Several scoring systems have been proposed to evaluate the amount of fibrosis in chronic hepatitis.(Table by Desmet, 1994)

Score Description Knodel Sciot and Desmet
0 No fibrosis No fibrosis None None
1 Mild fibrosis Fibrous portal
Periportal fibrous
portal tracts
2 Moderate fibrosis(blank) Porto-portal septa
(> 1 septum)
Periportal or portal-portal septa,
but intact architecture
3 Severe fibrosis Bridging fibrosis
(portal-portal or
portal-central linkage
Portocentral septa
(> 1 septum)
Fibrosis with architectural
distortion, but no
obvious cirrhosis
4 Cirrhosis Cirrhosis Cirrhosis Probable or definite

From: Desmet: Hepatology:(1994); 19:1513,; Knodell: Hepatology:(1981); 1:431,; Scheuer: J Hepatology:(1991); 13:372.

[Dr. Wu's Health Note- Home] [Taiwan Medical Network]
[Web sites for medical students][Curriculum Vitae ]

(By Jau-Shin Wu, M.D.; Posted Sep. 16, 1996; Revised May 12, 2009)

(TMN) Since June 09, 2002

(Dr. Wu's Liver D) Since Jan. 01, 2008

(Olddoc)Since Jan. 01, 2008

(TMN) Since Jan. 01, 2008