Prognosis of chronic hepatitis and cirrhosis

Prognosis of chronic hepatitis and cirrhosis

Dr. Wu's Liver diseases
for professionals (medical students and residents)

(by Jau-Shin WU, M.D., Ph.D.)

( Last updated Oct. 14, 2005 )

Prognosis of chronic hepatitis and cirrhosis

For consumers:

(Key words: chronic hepatitis, cirrhosis, prognosis)

10 yrs after the diagnosis of chronic hepatitis, 5% of HBV and 15% of HCV chronic hepatitis patient will develop into liver carcinoma.
The prognosis is worse in HCV patients than HBV patients.

**Prognosis of chronic hepatitis (10 yrs)**
	Cirrhosis	HCC	Clinical cure
HBV	17.3% (30/173)	4.6% ( 8/173)	38.2% (66/173)
HCV	29.7% (46/155)	14.8% (23/155)	2.6% ( 4/155)

Prognosis of cirrhosis (Oncogenesis) (%)
-	3 yr	5 yr	10 yr	15 yr
HBV (180)	7.2	14.2	27.2	27.2
HCV (349)	10.4	21.5	53.2	75.2

Prognosis of cirrhosis (survival rate) (%)
-	3 yr	5 yr	10 yr	15 yr
HBV ( ? )	91.7	87.1	73.1	68.6
HCV ( ? )	96.4	87.8	62.3	35.9

For professionals:

Prognosis of chronic hepatitis (10 yrs)
Cirrhosis HCC Clinical cure

HBV 17.3%
(30/173) 4.6%
( 8/173) 38.2%
(66/173)

HCV 29.7%
(46/155) 14.8%
(23/155) 2.6%
( 4/155)

M.Yano (J Clin Exp M, 171:1079, 1994)

Prognosis of cirrhosis (Oncogenesis) (%)
- 3 yr 5 yr 10 yr 15 yr

HBV (180) 7.2 14.2 27.2 27.2

HCV (349) 10.4 21.5 53.2 75.2

with diagnosis of HC / HB 529／795(2 - 17 yrs observstion)

Prognosis of cirrhosis (survival rate) (%)
- 3 yr 5 yr 10 yr 15 yr

HBV ( ? ) 91.7 87.1 73.1 68.6

HCV ( ? ) 96.4 87.8 62.3 35.9

Death rate 28.6% (227/795) (2-17 yr，Center value 5.8 yr)

H. Kumada (J Clin Exp M,171:1093, 1994)

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(By Jau-Shin Wu, M.D.;Posted Sep. 1996; Revised Apr. 24, 2003)